A team of researchers from the University of Minnesota and The Dow Chemical Company have discovered a new method for customizing ingredients that help oral medications dissolve in the body and be absorbed into the bloodstream. The materials discovered in this study could allow life-saving drugs to work faster and more efficiently.The University of Minnesota and Dow have filed a patent on the discovery that may also lower the cost to produce new medications.The research study is now online and is published in the current issue of the American Chemical Society’s ACS Central Science, a leading journal in the chemical sciences.One of the biggest challenges for pharmaceutical companies when developing oral medications is to ensure that the body will fully absorb the drug molecules. Many therapeutic structures do not easily dissolve on the molecular level, which means they are less effective. In that case, the dose must be increased for patients, which may increase side effects.”A way to explain the differences in solubility of medicines is to think of how sugar easily dissolves in water and is rapidly absorbed by your digestive system, whereas sand doesn’t dissolve in water and if swallowed, would pass right through the digestive system,” said Theresa Reineke, a chemistry professor in the University of Minnesota’s College of Science and Engineering and lead researcher on the study.
New Discovery Could Help Oral Medicines Work Better
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